Radicle Proof Engine™

We’ve pioneered the first ever easy path for supplements products to clinically prove their true effects beyond placebo.

AI-driven, virtual, D2C clinical trials at unprecedented affordability, speed, and scale
Objective evidence to enable strong claims
Deep customer insights to drive revenue and increase CLV

The Radicle Proof Engine delivers gold standard IRB-approved double-blind, randomized, placebo-controlled clinical trials for supplement brands, manufacturers, and ingredient suppliers.

Pioneering Proof-as-a-Service

The Radicle Proof Engine delivers standardized trials that test your effectiveness on any of the following outcomes:

  • Cognition
  • Energy
  • General Pain
  • Gut Health
  • Mood and Feelings of Anxiety
  • Quality of Life and Overall Health
  • Sleep
  • Stress

Products must be legal dietary supplements in orally ingestible form factors such as:

  • Capsules
  • Gummies
  • Tablets
  • Liquids
  • Lozenges
  • Strips
  • Powders
  • Softgels, etc.

Radicle Proof Engine™

Our Radicle Proof Engine enables validation of existing products in the market and discovery of the most effective products to bring to market.

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Radicle
Validation™

Radicle Validation is an Institutional Review Board (IRB)-approved, double-blind, randomized, placebo-controlled clinical trial to prove the true effects of your nonprescription supplement products.  

This gold-standard trial generates the most objective data to enable strong claims and establish unique credibility with all stakeholders, from customers and retailers, to healthcare providers and investors.  Products must already be sold in the market to enroll in Radicle Validation.  

Generate objective evidence to enable strong structure/function claims
Drive revenue and customer lifetime value (CLV)
Minimum: six-week study duration, two arms (one placebo and one active product), and 325 participants per arm
Growing number of study templates available, including pain, stress, sleep, anxiety, well-being, quality of life, fatigue and cognitive function
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Radicle
Discovery™

Radicle Discovery is a blinded, randomized controlled clinical trial enabling head-to-head comparisons of your nonprescription supplement products under development.  

Radicle Discovery allows you to explore multiple new formulations, form factors, and/or dosages to understand the true differences in effects and side effects.  Radicle Discovery trials can have up to six total arms.  

Rapidly compare multiple new formulations, form factors, and/or dosages
Guide customer and condition targeting
Accelerate new product development and bring the most effective product to market
Minimum: six-week study duration, two arms, and 325 participants per arm.
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The Radicle Way: A three-step path to clinically proven product claims

  1. Simply pick a product and condition to study.
  2. We handle everything else, from trial creation and recruitment to data collection and analysis.
  3. Receive actionable results in under 6-9 months that can enable strong claims, drive innovation and enable smart business decisions.

Pricing for standardized trials with more than 600 participants begin at less than $100k.

Our partners and clients
Clean Label Project logo proof
open book logo
nutraland logo
bioptimizers logo
rae logo proof
wholistic logo proof
anresco logo proof
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