Volunteer for history’s first 100% virtual, large scale clinical trials on supplements!

Radicle Science is recruiting volunteers for history’s largest and most innovative studies on nonprescription health and wellness products such as herbs, supplements, probiotics, and functional mushrooms. Our studies are 100% virtual and investigate the effects of these products for improving areas such as sleep, anxiety, pain, energy, mental clarity and focus.

By volunteering for a Radicle study, you’ll not only get to understand how these supplements work for your unique body but also contribute to science. Interested? Then sign up and be the first to know about new studies, before we recruit from the public.

How do Radicle Studies work?

Radicle Science studies are done from the comfort of your own home—they are 100% virtual! The process is just three steps:

  • Sign up and qualify
  • Take a baseline survey and get product shipped to your home
  • Complete short surveys for four to six weeks and get your personalized Personalized Participant Report
Image with a sample Radicle Rest Product pill bottle on the left hand, and a phone on the right hand showing an example of a participant pre-screener survey
Participant Feedback

What was the most enjoyable aspect of the study for you?

Radicle shape icon

“The most enjoyable aspect of participating in the study was [trying] a product that I have never considered trying before. It was important that I see if the product would aid in a good night’s sleep.”

Radicle shape icon

“I liked being part of a study and learning what would or wouldn’t work for my body…being able to help the community as a whole understand the benefit of CBD products and how they are a helpful go to product.”

Radicle shape icon

“…being part of a community dedicated to better living through natural / biochemistry. I’m a big fan of pioneers like Abram Hoffer and Roger Williams so keep up the vital work!”

Radicle shape icon

The most enjoyable aspect of the [study] was seeing the results that the product was able to produce.

Why should you sign up to be a Radicle study participant?

  • Help us make history by joining some of the first clinical trials conducted in the US on health and wellness products from the comfort of your home. These products are generally ignored by pharmaceutical research because they cannot be patented.

  • Receive a 4-6 week supply of a premium health and wellness product at no cost to you. All study products have been third-party tested to be free of contaminants.

  • Plant Icon

    Contribute to science and revolutionize the field of nonprescription health and wellness products which can bring better health to all.

  • Receive your personalized Personalized Participant Report at the end of the study so you can understand how the product uniquely affected YOU!

  • In collaboration with faculty from

Open Recruitment Studies

Feeling a little anxious lately?

Announcing Radicle Calm™

Radicle Science is recruiting volunteers for our upcoming study, called Radicle Calm. We’re researching health and wellness products containing ingredients such as CBD, nootropics (cognition enhancers) and adaptogens like functional (non-psychoactive) mushrooms and their effects on anxiety.

If you qualify and enroll, you’ll receive a six-week supply of a health and wellness product (at no cost to you) and a personalized Radicle Health Report when you complete the study. See if you qualify.

How’s your body feeling?

Announcing Radicle Relief™

Radicle Science is recruiting volunteers for our upcoming study, called Radicle Relief. We’re researching health and wellness products containing ingredients such as CBD, nootropics (cognition enhancers) and adaptogens like functional (non-psychoactive) mushrooms and their effects on pain.

If you qualify and enroll, you’ll receive a six-week supply of a health and wellness product (at no cost to you) and a personalized participant report when you complete the study. See if you qualify.

Having a hard time finding your keys?

Announcing Radicle Clarity™

Radicle Science is recruiting volunteers for our upcoming study, called Radicle Clarity. We’re researching health and wellness products containing adaptogens like functional (non-psychoactive) mushrooms and their effects on focus or mental clarity.

If you qualify and enroll, you’ll receive a six-week supply of a health and wellness product (at no cost to you) and a personalized participant report when you complete the study.

Looking to improve your health and wellness?

Announcing Radicle Health™

We’re researching health and wellness products containing ingredients such as CBD and their effects on health states such as sleep quality, energy levels, pain, and feelings of anxiety or stress.

If you qualify and enroll, you’ll receive a four-week supply of a health and wellness product (at no cost to you) and a personalized participant report when you complete the study.

Our studies fill up within a day or so. But we always email our Radicle Participants before we open recruitment to the general public. Be sure to sign up for our newsletter  to be the first to know! 

Sleep been off lately?

Announcing Radicle Rest™

Radicle Science is recruiting study volunteers for our upcoming study, called Radicle Rest. We’re researching health and wellness products containing ingredients such as nootropics (cognition enhancers) and adaptogens like functional (non-psychoactive) mushrooms and their effects on sleep quality.

If you qualify and enroll, you’ll receive a six-week supply of a health and wellness product (at no cost to you) and a personalized participant report when you complete the study.

Our studies fill up within a day or so. But we always email our Radicle Participants before we open recruitment to the general public. Be sure to sign up for our newsletter  to be the first to know! 

Study Participant FAQs

Your participation is 100% virtual. We ship the product directly to your home, and you share information about your health and your behaviors through our online surveys. All your information is kept strictly confidential.

To be the first to know about enrollment and sign up for future studies, please subscribe to our newsletter here. We’ll reach out when we begin recruitment. You’ll then be asked a few screening questions to see if you qualify. Thanks for your interest in helping us gather data on health and wellness products!

Radicle studies are short and most of them last about 4-6 weeks! We ask you to take your study product as directed during the study and answer the surveys that we send to you through email or text message. We’ll send you a final and feedback survey to take at the end. It’s so easy!

You will receive a Personalized Participant Report which provides insights based on your study responses and tells you how you did, along with the product for the study at no cost to you.

Of course! You can always share information about the study with your primary doctor or healthcare provider. You can continue to see your doctor throughout the study for routine visits and tests.

Our core focus is gathering clinical data to validate health and wellness products, the first of its kind! Our virtual, direct-to-consumer studies enable a smooth experience for participants, as well as enabling us to bring much needed equity and diversity into medical research. The unprecedented scale and reach of our studies finally enables inclusion of diverse ethnicities, genders, age groups, behavioral habits, and pre-existing health conditions to move us closer to personalized medicine for the population at large.

And unlike most studies, we share your results with you after the study in the form of a Personalized Participant Report, which not only summarizes your usage patterns over the course of the four-week study, but also compares your individual data to both the study population and relevant demographics and/or behavioral subsegments for actionable insights.